A phase 3, randomized, double-blind study of adjuvant immunotherapy with Nivolumab versus placebo after complete resection of stage IIB/C melanoma (CA209-76K) Protocolnummer: CA20976K EudraCT nummer: 2019-001230-34 METc nummer:…
A Phase 3, Open-label, Randomized Study of Nivolumab Combined with Ipilimumab versus Standard of Care Chemotherapy in Participants with Previously Untreated Unresectable or Metastatic Urothelial Cancer (CheckMate 901:…
Maintenance treatment with capecitabine and bevacizumab versus observation after induction treatment with chemotherapy and bevacizumab as first-line treatment in patients with advanced colorectal carcinoma, a randomised phase III…
De waarde van peri-operatieve systemische therapie in patiënten die cytoreductieve chirurgie en HIPEC ondergaan voor het peritoneaal gemetastaseerd colorectaal carcinoom: de multicenter, fase II-III, prospectieve, gerandomiseerde CAIRO6 studie….
De waarde van peri-operatieve systemische therapie in patiënten die cytoreductieve chirurgie en HIPEC ondergaan voor het peritoneaal gemetastaseerd colorectaal carcinoom: de multicenter, fase II-III, prospectieve, gerandomiseerde CAIRO6 studie….
Behandeling met cemiplimab van patiënten met lokaal vergevorderd of gemetastaseerd secundair angiosarcoom. Eudractnummer: 2020-005465-13 Samenvatting In deze fase II studie kunnen patiënten met een lokaal vergevorderd of gemetastaseerd…
CA209-214: A Phase 3, Randomized, Open-Label Study of Nivolumab Combined with Ipilimumab Versus Sunitinib Monotherapy in Subjects with Previously Untreated, Advanced or Metastatic Renal Cell Carcinoma Protocolnummer: CA209-214…
A Phase III randomized, 3-arm, open label, multicenter study of LGX818 plus MEK162 and LGX818 monotherapy compared with vemurafenib in patients with unresectable or metastatic BRAF V600 mutant…
Adjuvante Encorafenib en Binimetinib versus placebo in volledig gereseceerd BRAF V600E/K-gemuteerd stadiumIIB/C melanoom: een gerandomiseerd driedubbelblind fase III-onderzoek in samenwerking met de EORTC Melanoma Group. Protocolnummer: W00090GE303 /…
A phase III randomized double blind study of dabrafenib (GSK2118436) in COMBInation with trametinib (GSK1120212) versus two placebos in the ADjuvant treatment of high-risk BRAF V600 mutation-positive melanoma…
A Phase 3, Randomized, Double-blind, Controlled Study of Cabozantinib (XL184) vs. Prednisone in Metastatic Castrationresistant Prostate Cancer Patients who have Received Prior Docetaxel and Prior Abiraterone or MDV3100.
Development of a platform for next-generation DNA sequencing based personalized treatment for cancer patients: Protocol to obtain biopsies from patients with advanced (incurable) or metastatic cancer (CPCT –…
An open-label, dose-finding and proof of concept study of the PD-L1 probody™ therapeutic, CX-072, as monotherapy and in combination with yervoy (ipilimumab) or with zelboraf (vemurafenib) in subjects…
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Abemaciclib in Combination with Abiraterone plus Prednisone in Men with High-Risk Metastatic Hormone-Sensitive Prostate Cancer EU trial number: 2022-500461-28-06 Samenvatting…
A Phase 1/2, Open-label Study to Evaluate the Safety and Antitumor Activity of MEDI0680 (AMP-514) in Combination with Durvalumab versus Nivolumab Monotherapy in Subjects with Select Advanced Malignancies….
A phase III, randomized, open-label, controlled, multi center, global study of first-line MEDI4736 monotherapy and MEDI4736 in combination with tremelimumab versus standard of care chemotherapy in patients with…
A Phase 3, Interventional, Randomized, Multicenter, Open-Label Study of DCC-2618 vs Sunitinib in Patients with Advanced Gastrointestinal Stromal Tumors after Treatment with Imatinib Protocolnummer: DCC-2618-03-002 EudraCT nummer: 2018-001803-35…
A Phase 2, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of Trastuzumab Deruxtecan (T-DXd, DS-8201a) for the Treatment of Selected HER2 Expressing Tumors (DESTINY-PanTumor02) Protocolnummer D967VC00001…