Fase I studies

Fase I studies

LAG-3

7 januari 2022
ImmunoPET imaging with 89Zr-DFO-REGN3767 in patients with advanced solid cancer prior to and during treatment with cemipliamb with or without platinum-based chemotherapy. Samenvatting 89Zr-DFO-REGN3767 is een experimentele PET...
Bekijken

Potentia

3 september 2021
A Phase 1 Open-Label, Dose Escalation and Expansion Trial to Investigate the Safety, harmacokinetics and Pharmacodynamics of CB307, a Trispecific Humabody® T-cell Enhancer, in Patients with PSMA+ Advanced...
Bekijken

Dragonfly

30 augustus 2021
A Phase I/II, First-In-Human, Multi-Part, Open-Label, Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, Biological, and Clinical Activity of DF1001 in Patients With Locally Advanced or...
Bekijken

Destiny-PanTumor02

15 juni 2021
A Phase 2, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of Trastuzumab Deruxtecan (T-DXd, DS-8201a) for the Treatment of Selected HER2 Expressing Tumors (DESTINY-PanTumor02) Protocolnummer D967VC00001...
Bekijken

GO41596

3 juni 2021
A phase Ia/Ib, open-label, multicenter, global, dose-escalation study to evaluate the safety and pharmacokinetics of XmAb24306 as a single agent and in combination with atezolizumab in patients with...
Bekijken

DEBIO-0123

A phase 1 study of oral Debio 0123 in combination with carboplatin in patients with advanced solid tumors. Protocolnummer: Debio 0123-101 EudraCT nummer: 2018-003659-39 METc nummer: 2019/631 Samenvatting...
Bekijken

M15-913

An Open Label Phase 1, First-In-Human Study of TRAIL Receptor Agonist ABBV-621 in Subjects with Previously-Treated Solid Tumors and Hematologic Malignancies. M15-913 Protocolnummer: M15-913 Eudract nummer: 2016-003887-37 METc...
Bekijken

CD8 PET imaging studie (GENENTECH)

Een fase 1-2 immunoPET imaging studie met ZED88082A/CED88004S in patiënten voor en tijdens behandeling met 1) MPDL3280A of 2) PD-1 antilichaam met of zonder ipilimumab. Protocolnummer: Eudract nummer:...
Bekijken