Archief

ZEPHIR

A phase II prospective imaging study evaluating the utility of pre-treatment zirconium-89 labelled trastuzumab PET/CT and an early FDG-PET/CT response to identify patients with advanced HER-2 positive breast…

TULIP

A multi-centre, open-label, randomized clinical trial comparing the efficacy and safety of the antibody-drug conjugate SYD985 to physician’s choice in patients with HER2-positive unresectable locally advanced or metastatic…

G1T48

Phase 1, Open-Label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of Ascending Doses of G1T48 in Women with Estrogen Receptor-Positive, HER2-Negative Advanced Breast…

GDC-0810

An open-label, phase I/IIA study of GDC-0810 in postmenopausal women with locally advanced or metastatic estrogen receptor positive breast cancer (GO29642) SERD Genentech Protocolnummer: GO29642 Eudract nummer: 2014-004852-77…

AIPAC

Active Immunotherapy PAClitaxel: A multicentre, Phase IIb, randomized, double blind, placebo-controlled study in hormone receptor-positive metastatic breast carcinoma patients receiving IMP321 (LAG-31g fusion protein) or placebo as adjunctive…

Knowledge and attitudes regarding healthy lifestyle

IMPACT – Breast

Towards patient tailored cancer treatment supported by molecular imaging IMPACT: IMaging PAtients for Cancer drug selecTion – Metastatic Breast Cancer METcnummer: 2013/146 EudraCT nummer: 2013-000551041 Samenvatting Mogelijk zijn…

M12-914

A Phase 3 Randomized, Placebo-controlled Trial of Carboplatin and Paclitaxel With or Without Veliparib (ABT-888) in HER2-negative Metastatic or Locally Advanced Unresectable BRCA-associated Breast Cancer Protocolnummer: M12-914 EudraCT…

Breast Optical Imaging

Validation of Uptake of a VEGF-targeted Optical Fluorescent Imaging Tracer in Surgical Specimens of Breast Cancer and Application of Pre- and Intra-operative Human Molecular Fluorescence Imaging Techniques. A…

6x TCH, 11x Trastuzumab

Inclusie Hoog risico HER2+, ER+ mammacarcinoom:tumor >3cm e/o positieve klier (anders: APT schema) In deze setting heeft TCH de voorkeur boven AC-TH gezien de equivalente survival en minder…

Paclitaxel wekelijks + Trastuzumab (APT schema)

Inclusie Lager risico HER2+, ER+ mammacarcinoom, tumor ≤ 3 cm; N0, N0itc of 1 micrometastase (1). Bij bezwaren tegen chemotherapie kan bij T1bN0 HER2+ ER+ mammacarcinoom ook een…

6x TCH, 11x Trastuzumab

Inclusie Hoger risico HER2+ mammacarcinoom: tumor >3cm e/o positieve klier (anders: APT schema) In deze setting heeft TCH de voorkeur boven AC-TH gezien de equivalente survival en minder…

12x paclitaxel/trastuzumab, 13x trastuzumab (APT schema)

Inclusie Lager risico HER2+ mammacarcinoom, tumor ≤ 3 cm; N0, N0itc of 1 micrometastase(1). Er zijn beperkte data over HER2 gebaseerde therapie bij patiënten >70 jaar. Bij deze…